Module overview
Section 5 of 6 · Open sections

Required section · Section 5 of 6

Choose the Next Laboratory Action

Return to the case before reading the rationale. The evidence that matters is the opiate assay target, its 300 ng/mL cutoff, the separate negative oxycodone and fentanyl targets, the acceptable specimen context, the documented morphine, and the definitive analyte results. Rank explanations by what the actual panel can support. Do not add an explanation for an analyte that was not tested.

The fentanyl result means no assay signal met the cutoff for the tested fentanyl target in this specimen; it does not exclude exposure outside the target, cutoff, specimen timing, or detection window. It does not turn the opiate result into a fentanyl result, and a routine opiate screen would not substitute for it. Likewise, a negative oxycodone screen is bounded by that assay's target, cutoff, and collection timing. The laboratory action should remain tied to the ordered and tested panel.

The preferred action is to release the definitive result using approved local wording and communicate that morphine was detected within the definitive panel, with 6-acetylmorphine not detected. A recollection is not supported by the listed validity findings alone. A specific fentanyl result cannot be inferred from an opiate class reaction or from a fentanyl screen with no signal meeting its cutoff for its tested target. Match the action to the evidence, then stop at the method boundary.

Ordering exercise

Place the case review steps in the order that supports a bounded release decision.

  1. 1. Review definitive analytes

    Identify analyte-specific detections and limits of the tested panel.

  2. 2. Release bounded interpretation

    Use approved local language without inferring dose, impairment, or behavior.

  3. 3. Read assay targets and cutoffs

    Determine what each screen is designed to detect.

  4. 4. Review specimen context

    Use creatinine, specific gravity, pH, oxidant findings, collection facts, and local policy.

Knowledge checks

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Knowledge check 1

The documented morphine explains the opiate-class screen. Which next action best addresses the still-unexplained mental-status change?

Choose one option.

Section status

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