What this differential supports and what it does not

This case supports a representative manual differential with a 5% reactive-appearing lymphocyte subset included within the 24% total lymphocyte percentage and agreement between manual and automated proportions. It supports a flag-driven peripheral smear review, not a clinical diagnosis.

Use the laboratory's published reference ranges, locally validated review criteria, and analyzer instructions for use. Common adult absolute neutrophil and lymphocyte ranges are often cited as about 1,500 to 8,000 and 1,000 to 4,000 cells per microliter, respectively, but age, population, analyzer, and laboratory verification matter. CLSI H20 is a reference-method and instrument-evaluation standard, not a universal patient-reporting interval. The exact band policy, count extension criteria, and manual-versus-automated agreement limits are local policy fields.

Generic automated differential behavior is used here because no analyzer, reagent, calibrator, or software version is specified. Review this content when the laboratory changes its local differential procedure, analyzer flags, reference intervals, or review criteria. The source frame is United States CLIA, CAP, and CLSI, not ISO 15189. Separate the measured percentage, the observed morphology, and the action your procedure requires.