Module HEME-12 · Version 1.0
Anemia as an Index-Driven Problem
Organize anemia with hemoglobin, MCV, RDW, reticulocyte response, and peripheral smear findings before selecting focused follow-up.
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Who this module is for
Medical laboratory scientists and trainees who review CBC, reticulocyte, and smear results on shift.
Learning objectives
- Use absolute reticulocyte count (ARC) as the primary marrow-response measure with declared timing and anemia context.
- Use MCV, RDW, smear morphology, and ARC to organize—not diagnose—anemia patterns.
- Calculate and integrate a novel anemia case with one defensible next test or an explicit missing-data outcome.
How completion works
Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.
Sources
14 sources
1. World Health Organization. Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. 2024.
Source note · professional society guidance
2. Clinical and Laboratory Standards Institute. H44-A2: Methods for Reticulocyte Counting. 2004.
Source note · consensus standard
3. Palmer L, Briggs C, McFadden S, et al. ICSH recommendations for morphology nomenclature and grading. Int J Lab Hematol. 2015;37:287-303.
Source note · consensus standard
4. College of American Pathologists. Laboratory Accreditation Program Standards for Accreditation. Current edition.
Source note · accreditation standard
5. Turner J, Parsi M, Badireddy M. Anemia. StatPearls. Updated 2023.
Source note · peer-reviewed literature
6. Conrad ME. Anemia. Clinical Methods. 3rd ed. 1990.
Source note · peer-reviewed literature
7. KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Kidney Int Suppl. 2012;2:279-335.
Source note · professional society guidance
8. Barcellini W, Fattizzo B. Clinical applications of hemolytic markers. Dis Markers. 2015;2015:635670.
Source note · peer-reviewed literature
9. Spadaro S, et al. Effects of blood transfusion on RDW. Transfusion. 2018;58:1863-1869.
Source note · peer-reviewed literature
10. Centers for Medicare & Medicaid Services. 42 CFR 493.1253. Establishment and verification of performance specifications.
Source note · federal regulation
11. Centers for Medicare & Medicaid Services. 42 CFR 493.1255. Calibration and calibration verification procedures.
Source note · federal regulation
12. Centers for Medicare & Medicaid Services. 42 CFR 493.1256. Control procedures.
Source note · federal regulation
13. Centers for Medicare & Medicaid Services. 42 CFR 493.1269. Hematology.
Source note · federal regulation
14. Sysmex Corporation. Advanced Reticulocyte Parameters: XN/XN-L Series. Current web resource.
Source note · manufacturer labeling