Catalog

HEME-10

Version 1.0

Aggregation and Distortion: Rouleaux, Agglutination, and Artifacts

Use smear distribution and CBC plausibility to distinguish rouleaux, cold-reactive agglutination, and preparation artifacts, then choose only validated corrective actions.

HEME-17

Version 1.0

Alpha- and Beta-Thalassemia Patterns

Use CBC indices, smear findings, hemoglobin fractions, age, iron status, and bounded follow-up to recognize thalassemia patterns without assigning genotype from one result.

HEME-12

Version 1.0

Anemia as an Index-Driven Problem

Organize anemia with hemoglobin, MCV, RDW, reticulocyte response, and peripheral smear findings before selecting focused follow-up.

HEME-02

Version 1.0

Bone Marrow Collection and Basic Morphologic Review

Evaluate marrow aspirate and core-related specimen quality, allocate material deliberately, and complete an introductory, preparation-aware morphologic review without issuing a diagnosis.

HEME-21

Version 1.0

Chromatin, Cytoplasmic Inclusions, and Findings That Require Escalation

Use observable leukocyte morphology, CBC correlation, and local policy to describe high-concern findings without forcing an image-only diagnosis.

HEME-25

Version 1.0

Chronic Myeloid Leukemia: Pattern, Confirmation, and Molecular Monitoring

Recognize a CML-supportive blood pattern, select bounded BCR::ABL1 confirmation, and protect molecular trend interpretation from method-related error.

HEME-22

Version 1.0

Flagged Neutrophilia: A Bounded CBC and Smear Workflow

Use one locally governed workflow to verify a flagged neutrophilia result, calculate and compare the local ANC, resolve the immature-granulocyte flag on a Wright-Giemsa smear, and route rather than diagnose.

HEME-28

Version 1.0

Flow Cytometry Fundamentals and Gating

Learn how a flow cytometer records single-cell events and how a reproducible gate hierarchy, controls, and stated denominator support a bounded hematology result.

HEME-01

Version 1.0

Hematopoietic Lineages from Stem Cell to Peripheral Blood

Use a practical lineage map and visible maturation features to orient cells from marrow production to the peripheral blood film.

HEME-32

Version 1.0

Hematopoietic Stem-Cell Transplantation: A Laboratory Timeline

Follow the laboratory questions that arise before collection, during conditioning and infusion, through engraftment, and during post-transplant monitoring after hematopoietic stem-cell transplantation (HSCT), connecting collection, product testing, engraftment, chimerism, disease monitoring, transfusion support, and complication workups within stated method limits.

HEME-18

Version 1.0

Hemoglobin S Disorders and Common Analytical Patterns

Interpret HbS-containing patterns with fraction accounting, paired methods, morphology, age, and transfusion history while keeping genotype confirmation bounded.

HEME-15

Version 1.0

Hemolytic and Other Nonneoplastic Red-Cell Disorders

Use an integrated laboratory pattern to recognize increased red-cell destruction, separate it from specimen hemolysis, and choose bounded follow-up.

HEME-06

Version 1.0

Histograms, Scattergrams, and Analyzer Flags

Use declared Sysmex XN-series WDF/WNR and impedance evidence with CBC results, specimen inspection, and labeled smear review to make a validated local laboratory decision.

HEME-16

Version 1.0

How Hemoglobin Analysis Methods Work

Compare the evidence produced by major hemoglobin analysis methods, recognize method limits, and select a bounded confirmatory action.

HEME-29

Version 1.0

Introductory Immature B-Lineage Flow Case

Use declared sequential gates, an immature B-cell comparator, and bounded correlation to describe one immature B-lineage population without assigning a final disease entity.

HEME-19

Version 1.0

Iron Studies and Hereditary Hemochromatosis

Interpret serum iron, transferrin saturation, ferritin, inflammatory context, liver injury, and targeted HFE testing without treating a single result as proof of iron overload.

HEME-14

Version 1.0

Macrocytic Anemia Patterns

Organize macrocytosis with the CBC, peripheral smear, reticulocytes, nutrient markers, chemistry, and escalation findings without turning a pattern into a diagnosis.

HEME-09

Version 1.0

Membrane, Fragmentation, and Oxidative Red-Cell Morphology

Identify selected red-cell forms from visible features, standardize a schistocyte estimate, and choose a bounded review action.

HEME-13

Version 1.0

Microcytic Anemia Patterns

Use CBC indices, peripheral-smear findings, iron studies, and inflammation context to separate common microcytic-pattern families and choose a bounded next laboratory action.

HEME-26

Version 1.0

Myelodysplastic Neoplasms: Building an Integrated Workup

Recognize concerning cytopenia and dysplasia patterns, exclude common mimics, and select the marrow and ancillary evidence needed for integrated MDS classification.

HEME-27

Version 1.0

Myeloproliferative Neoplasms: Integrated Pattern Evaluation

Recognize sustained count and morphologic patterns that support a bounded MPN workup, then integrate molecular and marrow evidence without overcalling an entity.

HEME-03

Version 1.0

Normal Red Cells and Platelets

Establish a defensible visual baseline for normal red-cell and platelet backgrounds before naming abnormalities.

HEME-04

Version 1.0

Normal White Cells and the Differential

Identify normal leukocytes, count a representative manual differential, and reconcile it with an automated result using a flagged specimen.

HEME-30

Version 1.0

Pediatric Anemia and Lead-Related Findings

Apply age-specific laboratory context to pediatric anemia patterns and handle blood-lead screening results without overstating what the result establishes.

HEME-31

Version 1.0

Pediatric Leukemia and Hemoglobinopathy Cases

Interpret pediatric leukemia and hemoglobinopathy cases by integrating age-specific CBC and smear evidence, flow context, newborn hemoglobin patterns, transfusion history, specimen stewardship, and urgent communication boundaries.

HEME-20

Version 1.0

Reactive Granulocyte Changes

Classify common reactive neutrophil changes with the CBC differential, specimen age, film quality, and local review policy.

HEME-05

Version 1.0

Reading the CBC through Its Indices

Read measured and calculated complete blood count parameters as related evidence, then choose a bounded review action.

HEME-24

Version 1.0

Recognizing Acute Leukemia Patterns

Recognize CBC, analyzer, and peripheral-smear patterns concerning for acute leukemia; protect material for ancillary studies; and communicate urgently without assigning a final subtype from morphology alone.

HEME-11

Version 1.0

Red-Cell Inclusions and What They Represent

Use morphology, stain selection, and bounded interpretation to distinguish common red-cell inclusions from look-alikes.

HEME-08

Version 1.0

Red-Cell Size, Color, and Distribution

Use the monolayer, CBC indices, histogram shape, and specimen context to describe red-cell size, hemoglobinization, and population distribution without assigning an unsupported cause.

HEME-23

Version 1.0

True versus Spurious Thrombocytopenia

Confirm whether a low platelet count is analytically reliable before it is released or used for urgent communication. Use specimen evidence, analyzer clues, smear distribution, and validated alternate methods to separate clumping and other analytical causes from true thrombocytopenia.

HEME-07

Version 1.0

When CBC Results Are Spurious

Use CBC internal consistency, specimen evidence, analyzer information, and validated verification methods to recognize and investigate spurious results before release.