Module HEME-29 · Version 1.0
Introductory Immature B-Lineage Flow Case
Use declared sequential gates, an immature B-cell comparator, and bounded correlation to describe one immature B-lineage population without assigning a final disease entity.
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Who this module is for
Medical laboratory scientists and pathology trainees who have completed introductory flow cytometry and morphology modules.
Learning objectives
- Define a population by sequential gates, parent denominator, event count, scatter, and coordinated marker findings.
- Compare an immature B-lineage phenotype with the hematogone continuum without inferring coexpression from marginal marker results.
- Issue a bounded phenotype description that preserves negative-finding and specimen limitations and names required correlation.
How completion works
Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.
Sources
3 sources
1. Clinical and Laboratory Standards Institute. Clinical Flow Cytometric Analysis of Neoplastic Hematolymphoid Cells. 2nd ed., CLSI guideline H43-A2, reaffirmed 2017.
Source note · consensus standard
2. Raval A, et al. Analytical Appraisal of Hematogones in B-ALL MRD Assessment. Cureus. 2024;16:e54869. doi:10.7759/cureus.54869.
Source note · peer-reviewed literature
3. College of American Pathologists. Hematology, Coagulation, and Clinical Microscopy Checklist, HEM.36325 Correlation of Results (Phase I). CAP Accreditation Program, 12.09.2025 edition.
Source note · accreditation standard