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Module HEME-30 · Version 1.0

Pediatric Anemia and Lead-Related Findings

Apply age-specific laboratory context to pediatric anemia patterns and handle blood-lead screening results without overstating what the result establishes.

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Who this module is for

Medical laboratory scientists and trainees who interpret or release pediatric hematology and blood-lead results.

Learning objectives

  • Use age-appropriate hemoglobin, mean corpuscular volume, reticulocyte, and differential expectations.
  • Differentiate common iron-deficiency and thalassemia-pattern features in children.
  • Explain venous confirmation, blood-lead reference value meaning, and specimen contamination control.

How completion works

Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.

Sources

10 sources

  1. 1. Tahmasebi H, Higgins V, Bohn MK, Hall A, Adeli K. CALIPER Hematology Reference Standards (I): Improving Laboratory Test Interpretation in Children (Beckman Coulter DxH 900-Core Laboratory Hematology System). American Journal of Clinical Pathology. 2020;154:330-341. doi:10.1093/ajcp/aqaa059.

    Source note · peer-reviewed literature

  2. 2. Widness JA. Pathophysiology of anemia during the neonatal period, including anemia of prematurity. Neoreviews. 2008;9:e520-e525. PMCID: PMC2867612.

    Source note · peer-reviewed literature

  3. 3. World Health Organization. Guideline on haemoglobin cutoffs to define anaemia in individuals and populations. 2024.

    Source note · professional society guidance

  4. 4. World Health Organization. WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. 2020.

    Source note · professional society guidance

  5. 5. Özdemir N. Iron deficiency anemia in infancy, childhood, and adolescence. Turkish Archives of Pediatrics. 2023;58:358-362. PMCID: PMC10440944.

    Source note · peer-reviewed literature

  6. 6. Joishy SK, Shafer JA, Rowley PT. The contribution of red cell morphology to the diagnosis of beta-thalassemia trait. Blood Cells. 1986;11:367-374. PMID:3742056.

    Source note · peer-reviewed literature

  7. 7. Cheson BD, Rom WN, Webber RC. Basophilic stippling of red blood cells: a nonspecific finding of multiple etiology. American Journal of Industrial Medicine. 1984;5:327-334. doi:10.1002/ajim.4700050409.

    Source note · peer-reviewed literature

  8. 8. Clinical and Laboratory Standards Institute. C40Ed3: Measurement Procedures for the Determination of Lead in Whole Blood. 3rd ed. April 2024.

    Source note · consensus standard

  9. 9. Centers for Disease Control and Prevention. Recommended actions based on blood lead level. Updated 2025-08-21.

    Source note · federal guidance

  10. 10. U.S. Food and Drug Administration. Risk of false positive lead test results with certain capillary blood collection tubes used with Magellan Diagnostics LeadCare testing systems. Updated 2026-02-03.

    Source note · federal guidance