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Module UBF-01 · Version 1.0

From Collection to Analysis: Protecting the Urine Specimen

A urinalysis result is only as good as the specimen behind it. The path from collection purpose through labeling, transport, storage, and processing determines whether a urine specimen can be accepted, rejected, recollected, or released with qualification before its analytical findings are trusted.

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Who this module is for

Laboratory professionals and students learning urinalysis and body fluid preanalytics, with basic specimen handling and patient identification already in place.

Learning objectives

  • Distinguish clean-catch, catheter-port, timed, first-morning, random, and other urine collection purposes and what each is fit to answer.
  • Predict how elapsed time, temperature, light exposure, contamination, and evaporation can change urine cells, casts, bacteria, pH, glucose, bilirubin, urobilinogen, ketones, and concentration.
  • Apply a supplied acceptance, rejection, or qualification policy to accept, reject, recollect, or release a urine specimen with qualification, and explain the evidence behind the decision.

How completion works

Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.

Sources

13 sources

  1. 1. Centers for Medicare & Medicaid Services, 42 CFR 493.1242, Standard: Specimen submission, handling, and referral, current eCFR text. https://www.ecfr.gov/current/title-42/chapter-IV/subchapter-G/part-493/subpart-K/section-493.1242.

    Source note · federal regulation

  2. 2. Clinical and Laboratory Standards Institute, PRE05: Processes for the Collection of Urine Specimens, 1st ed., 2024, ISBN 978-1-68440-235-9. https://clsi.org/shop/standards/pre05/.

    Source note · consensus standard

  3. 3. Clinical and Laboratory Standards Institute, PRE01: Patient and Laboratory Specimen Identification Processes, current edition. https://clsi.org/standards/products/general-laboratory/documents/pre01/.

    Source note · consensus standard

  4. 4. Centers for Disease Control and Prevention, Summary of Recommendations: Guideline for Prevention of Catheter-Associated Urinary Tract Infections (2009), recommendation III.U, page reviewed March 25, 2024. https://www.cdc.gov/infection-control/hcp/cauti/summary-of-recommendations.html.

    Source note · professional society guidance

  5. 5. National Institute of Diabetes and Digestive and Kidney Diseases, Instructions for 24-Hour Urine Collection, HALT-PKD Form 37A. https://repository.niddk.nih.gov/media/studies/halt_pkd_a/Forms/F037A%20Instructions%20for%2024-Hour%20Urine%20Collection.pdf.

    Source note · professional society guidance

  6. 6. Roche Diagnostics, Combur-Test strip method sheet, current controlled revision required for the exact strip and reader. https://elabdoc-prod.roche.com/eLD/api/downloads/4266ba8e-2fbe-eb11-0591-005056a71a5d?countryIsoCode=se.

    Source note · manufacturer labeling

  7. 7. Dolscheid-Pommerich RC, et al. Evaluation of the appropriate time period between sampling and analyzing for automated urinalysis. Biochemia Medica. 2016;26:82-89. https://pmc.ncbi.nlm.nih.gov/articles/PMC4783094/.

    Source note · peer-reviewed literature

  8. 8. Delanghe J, Speeckaert M. Preanalytical requirements of urinalysis. Biochemia Medica. 2014;24:89-104. https://pmc.ncbi.nlm.nih.gov/articles/PMC3936984/.

    Source note · peer-reviewed literature

  9. 9. Cook JD, et al. Urine pH: the effects of time and temperature after collection. Journal of Analytical Toxicology. 2007;31:486-496. https://pubmed.ncbi.nlm.nih.gov/17988463/.

    Source note · peer-reviewed literature

  10. 10. Eksioglu MK, et al. The effectiveness of BD Vacutainer Plus Urinalysis Preservative Tubes in preservation of urine for chemical strip analysis and particle counting. Biochemia Medica. 2016;26:224-232. https://pmc.ncbi.nlm.nih.gov/articles/PMC4910281/.

    Source note · peer-reviewed literature

  11. 11. College of American Pathologists. All Common Checklist, COM.06100 Primary Specimen Container Labeling (Phase II). CAP Accreditation Program, 12.09.2025 edition.

    Source note · accreditation standard

  12. 12. College of American Pathologists. All Common Checklist, COM.06300 Specimen Rejection Criteria (Phase II). CAP Accreditation Program, 12.09.2025 edition.

    Source note · accreditation standard

  13. 13. College of American Pathologists. Laboratory General Checklist, GEN.40490 Patient Identification (Phase II). CAP Accreditation Program, 12.09.2025 edition.

    Source note · accreditation standard