Module GLP-12 · Version 1.0
Regression and Practical Laboratory Math
Work the calculations that come up every shift, dilutions, recoveries, and percent bias, then read a method-comparison scatter plot without mistaking a strong correlation for proven agreement.
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Who this module is for
Medical laboratory scientists and laboratory technicians performing bench calculations and reviewing method-comparison data
Learning objectives
- Calculate dilutions, concentrations, unit conversions, ratios, percent difference, recovery, and carryover using dimensional checks
- Interpret slope, intercept, residuals, confidence intervals, and scatter plots from a method-comparison study
- Distinguish correlation from agreement and identify outliers, nonlinearity, or heteroscedasticity in a residual plot
How completion works
Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.
Sources
10 sources
1. Johnson R. Assessment of Bias with Emphasis on Method Comparison. Clinical Biochemist Reviews. 2008;29(Suppl 1):S37-S42.
Source note · peer-reviewed literature
2. Clinical and Laboratory Standards Institute. EP09, Measurement Procedure Comparison and Bias Estimation Using Patient Samples, 3rd ed., corrected 2018.
Source note · consensus standard
3. Clinical and Laboratory Standards Institute. EP06, Evaluation of Linearity of Quantitative Measurement Procedures, 2nd ed., 2020.
Source note · consensus standard
4. Clinical and Laboratory Standards Institute. EP15, User Verification of Precision and Estimation of Bias, 3rd ed., reaffirmed 2019.
Source note · consensus standard
5. Clinical and Laboratory Standards Institute. EP10, Preliminary Evaluation of Quantitative Medical Laboratory Measurement Procedures, 4th ed., 2024.
Source note · consensus standard
6. Centers for Medicare & Medicaid Services. 42 CFR 493.1253, Standard: Establishment and verification of performance specifications.
Source note · federal regulation
7. Centers for Medicare & Medicaid Services. 42 CFR 493.1255, Standard: Calibration and calibration verification procedures.
Source note · federal regulation
8. College of American Pathologists. Accreditation Checklists.
Source note · accreditation standard
9. American Diabetes Association Professional Practice Committee. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes, 2026. Diabetes Care. 2026;49(Suppl 1):S27-S49.
Source note · professional society guidance
10. LatticeMLS. GLP-12 calculation conventions. Internal synthesis based on declared calculation definitions and cited sources.
Source note · module-authored