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Opening laboratory problem

A Romanowsky-stained peripheral smear is reviewed after an RBC morphology flag. The field contains occasional round dense purple bodies and small peripheral granular clusters. An inclusion is supported intracellular material within an intact RBC; stain precipitate or a slide overlay near a cell is a look-alike until focus and repeated fields establish its relationship to the cell.

Describe number, shape, border, distribution, neighboring RBCs, and routine-stain appearance before naming a structure. Routine morphology is not an analyzer measurement and does not establish a final diagnosis. No morphology image is presented for the guided case; its table records matched routine and Perls observations rather than presenting an image as patient evidence.

Illustrative drawing — this picture was drawn rather than captured.

Chart shows hemoglobin 9.8 g/dL below local interval 12.0 to 16.0, hematocrit 29.6 percent, MCV 91 fL, and platelets 468 times 10 to the ninth per liter.
Figure 1CBC context for the guided case; intervals are local intervals.
Case collected 09:10 and reviewed 10:05.
TestResultLocal interval
Hemoglobin9.8 g/dL12.0-16.0 g/dL
Hematocrit29.6%36.0-46.0%
MCV91 fL80-100 fL
Platelets468 × 10^9/L150-400 × 10^9/L

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Knowledge check 1

What does a peripheral smear inclusion observation establish?

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