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Module UBF-03 · Version 1.0

When the Dipstick and the Patient Do Not Agree

A worked approach to urine results where chemical pads, sediment microscopy, and patient history point in different directions. Covers what each pad actually measures, the specimen and analytical variables that create a mismatch, and how to choose a repeat, alternate-method, or recollection step that the evidence actually supports.

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Who this module is for

Clinical laboratory scientists and students who already read a urine chemistry strip and a urine sediment and want to reason through a discordant panel.

Learning objectives

  • Identify expected chemical-microscopic correlations and meaningful exceptions
  • Rank preanalytical, analytical, and physiological causes of a discordant urinalysis panel
  • Select a repeat, confirmatory, alternate-method, or recollection step that the evidence supports

How completion works

Mark every required section done and answer every knowledge check in those sections correctly. The final save completes the module automatically.

Sources

10 sources

  1. 1. Siemens Healthcare Diagnostics. Multistix 10 SG, Multistix 8 SG, Labstix, Uristix Reagent Strips: Instructions for Use, document 11306392 Rev. A, July 2017.

    Source note · manufacturer labeling

  2. 2. Roxe DM. Urinalysis. In: Walker HK, Hall WD, Hurst JW, eds. Clinical Methods: The History, Physical, and Laboratory Examinations, 3rd ed. Butterworths; 1990.

    Source note · laboratory reference

  3. 3. Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease.

    Source note · professional society guidance

  4. 4. Sethi I, Goldwater E, Shutty C, Flynn E, Henner D. Is specific gravity a good estimate of urine osmolality? J Clin Lab Anal. 2010;24:426-430.

    Source note · peer-reviewed literature

  5. 5. College of American Pathologists. Urinalysis Checklist, URN.30425 Microscopic Exam Correlation (Phase II). CAP Accreditation Program, 12.09.2025 edition.

    Source note · accreditation standard

  6. 6. Electronic Code of Federal Regulations. 42 CFR Section 493.1253, Standard: Establishment and verification of performance specifications.

    Source note · federal guidance

  7. 7. Electronic Code of Federal Regulations. 42 CFR Section 493.1256, Standard: Control procedures.

    Source note · federal guidance

  8. 8. Clinical and Laboratory Standards Institute. PRE05, Processes for the Collection of Urine Specimens, 1st ed., 2024.

    Source note · consensus standard

  9. 9. Clinical and Laboratory Standards Institute. EP07, Interference Testing in Clinical Chemistry, 3rd ed., reaffirmed October 2022.

    Source note · consensus standard

  10. 10. Simerville JA, Maxted WC, Pahira JJ. Urinalysis. StatPearls. Updated 2023.

    Source note · laboratory reference