Required section · Section 3 of 6

Match the assay to the question

Adult eGFR here uses the 2021 CKD-EPI creatinine equation with age, sex, standardized creatinine, and no race term. A creatinine-cystatin C estimate can confirm eGFR when creatinine is unreliable, including unusual muscle mass. eGFR remains an estimate rather than a direct nephron count.

ACR measures albumin and is preferred for CKD risk classification. PCR measures total protein and is not a direct substitute for ACR. Timed collection reports absolute excretion but can be incomplete or inaccurate. Dipstick grade is product- and method-specific; it is not a concentration-normalized ACR or PCR result.

The conventional dipstick protein pad is albumin-predominant and can miss A2 albuminuria, globulins, and light chains. SSA detects albumin and non-albumin protein broadly, so negative dipstick with SSA turbidity needs a local-algorithm review. Use ACR for albumin classification and investigate discordance.

Methods and discordance clues
Method	Measures	Limitation
ACR	Albumin	Not total protein
PCR	Total protein	Not albumin-specific
Dipstick protein	Albumin-predominant dye response	Can miss A2 and light chains
Blood pad	Heme activity	Cannot identify intact RBCs

Knowledge checks

Reading and checks are open. Sign in only to save.

Knowledge check 1

Dipstick protein is negative but SSA is turbid. What is the next interpretation?

Choose one option.

Consider non-albumin protein or SSA interference under the local reflex algorithm.

Exclude protein.

Assign A1 from the dipstick.

Knowledge check 2

Under the illustrative local microscopy rule, what does blood 2+ with 0–2 RBC/hpf mean?

Choose at least 4 options.

Section status

Finish this section

Reading and checks are open. Sign in only to save.

The module finishes after every required section is marked done and every check in those sections is correct.