Required section · Section 4 of 6
Work the case from chemistry to sediment
The first-morning clean-catch specimen was collected at 08:10, received at 08:40, and tested within the analyzer stability window. Creatinine was enzymatic and IDMS-traceable at 1.4 mg/dL against a local 0.6-1.3 mg/dL interval. eGFRcr 52 mL/min/1.73 m^2 is G3a.
ACR 145 mg/g is A2. PCR is reported as 210 mg/g; this package supplies no source-backed PCR decision threshold, so interpretation depends on the laboratory's local PCR interval. Protein 1+ is a product-specific dipstick grade, not a concentration-normalized ACR/PCR result. Repeat first-morning ACR is needed before treating albuminuria as established.
Under the illustrative local microscopy rule, blood 2+ with 3–5 RBC/hpf supports intact-RBC hematuria. A 2+ blood pad with only 0–2 RBC/hpf would be discordant and would raise hemoglobin, myoglobin, lysed cells, or interference. Granular casts provide renal-parenchymal context; muddy-brown granular casts are the specific morphology clue for tubular injury, not a synonym for every granular cast. Absence of RBC casts on one preparation does not rule out glomerular bleeding. Record corroborating and limiting evidence separately.
Illustrative drawing — this picture was drawn rather than captured.
Illustrative drawing — this picture was drawn rather than captured.
| Study | Result | Method | Anchor |
|---|---|---|---|
| Creatinine | 1.4 mg/dL | Enzymatic, IDMS-traceable | Interval 0.6-1.3 mg/dL |
| eGFRcr | 52 mL/min/1.73 m^2 | 2021 CKD-EPI | G3a |
| ACR | 145 mg/g | First-morning spot | A2 |
| PCR | 210 mg/g | Reflex ratio | Interpret using local PCR interval |
| Sediment | RBC 3-5/hpf; granular casts 1-2/lpf | Centrifuged preparation | Illustrative local rule: supports intact-RBC hematuria |
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