Required section · Section 5 of 6
Learner decision: choose the defensible action
Review five preparations in this complete text scenario: (1) particulate crush A has intact nuclei and cytoplasm and supports the differential; (2) crush B has smeared nuclei from excess pressure and is limited by crush artifact; (3) the wedge trail is hemodilute and cannot substitute for particle review; (4) the touch imprint was made before fixation and supplies rapid core cytology; and (5) the 1.8 cm core has adequate evaluable marrow despite being shorter than 2 cm. Select crush A for the differential and record each other preparation's stated role or limitation.
The procedure team reports that only one anticoagulated aliquot remains and conventional cytogenetics is requested. Choose sodium heparin for that aliquot, then document that molecular testing needs a separately collected EDTA aliquot if required. Do not invent a microbiology or biobanking tube route. Those routes depend on the receiving laboratory and local policy.
Write a bounded adequacy statement: particulate aspirate with visible spicules; differential based on a well-prepared particle crush; intact 1.8 cm core with evaluable marrow; and iron stain interpretable because the positive control worked. This supports an introductory morphologic correlation, not blast classification, fibrosis grading, cytogenetic interpretation, or a disease diagnosis. Release the condition of the preparation with the result, not an unqualified conclusion from a compromised field.
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